Funders › MN › A Breath of Hope Lung Foundation › 2021
Grants paid by A Breath of Hope Lung Foundation, tax year 2021
EIN 30-0475578 · Bloomington, MN · Form 990, Schedule I · NTEE G123
In tax year 2021, A Breath of Hope Lung Foundation (EIN 30-0475578) reported 2 grants paid totaling $150,000. Dataset version 2026.09.0, built 2026-09-03.
Every grant, 2021
| Tax year | Recipient | Match | Amount | Type | Purpose | Source filing |
|---|---|---|---|---|---|---|
| 2021 | Whitehead Institute of Biomedical Research Cambridge, MA | A | $75,000 | paid | This research project focuses on improving lung cancer outcomes with two aims: 1) To determine the mechanism by which macrophage activation enhances the response to EGFR TKIs; and 2: To investigate the anti-tumor efficacy of EGFR TKIs in combination with macrophage-directed therapies in xenograft models. | 202221229349301267 |
| 2021 | University of Texas Southwestern Dallas, TX | A | $75,000 | paid | The research project is seeking to understand the role of Telmerase that is expressed by most human cancers, particularly small cell lung cancer. We will target an essential survival mechanism of tumor cells to activate protective antitumor immunity and immune memory. We hypothesize that sytosolic DNA resulting from targeting telmerase with 6TdG treatment induces the cGAS/STING pathway, leading to enhanced antigen presentation and cyokine expression from tumors and dendritic cells (DC), causing the expansion and activation of tumor-specific T cells. If successful, our studies will guide the design of clinical trials. Given that NIH considers SCLC a recalcitrant disease, we believe SCLCs can easily be prioritized to be one of the first cancers to test 6TdG as these tumors do not have effective treatments currently. If we can generate strong preclinical evidence with this proposal, 6TdG can rapidly move in this subset in the clinic. | 202221229349301267 |
Match tier: A Reported EIN · B Exact name and place · C Strong name match · D Probable name match · U Unresolved. Tiers C and D are inferred, not reported; see how matching works.
Recipient matching for this dataset version has not yet completed its independent precision check. Tier A rows carry the EIN the filer reported; tiers B–D are the matcher's inference and should be read as leads until the check is published on the methodology page.
Derived from IRS Form 990 e-file XML. Dataset version 2026.09.0, built 2026-09-03. All years for this funder.
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